What Are Aptamers?
HIGH Affinity. HIGH Specificity.
Aptamers (synthetic antibodies) are stable DNA or RNA ligands that bind with high affinity and specificity to target antigens such as small molecules, peptides, proteins, cells, and tissues. For example, RNA aptamers have been generated that exhibit greater than 10,000-fold binding affinity for theophylline over caffeine, which differ only by a few atoms. Recently, a DNA aptamer has been developed with 250,000-fold specificity against the same small molecules.
Aptamer products can be used as research agents, diagnostics, biosensors, and tools for biomarker or drug discovery. Aptamers can also be used for bioindustrial applications and targeted therapeutics.
Antibody problems? Have difficult targets to develop effective ligands or antibodies? What if an antibody doesn't exist for your target or antigen?
No problem. Let Aptagen provide you with an alternative — the aptamer. You've heard about this new technology. Now, try it.
What is an aptamer?
Aptamers (synthetic antibodies) are stable single-stranded DNA, RNA, or peptide molecules capable of binding to their target antigen with high affinity and specificity. Aptamers have been developed against a wide variety of targets ranging from small organics to large proteins.
Benefits
- Manufacturing costs and time are lower compared to monoclonal antibody production.
- Once the aptamer sequence is known, it can be produced on the fly using an oligo synthesizer to meet immediate needs.
- Easy to label with reporters, enzymes, or fluorescent tags.
Aptamers Against Virtually Any Target
Proteins. Organics. Toxins. Cells. Tissues. Aptamers can be selected against an enormous range of targets through an in vitro selection process.
Explore Aptamer Applications
HIGH Affinity. HIGH Specificity.
Have a difficult target? Let Aptagen develop an aptamer for it.
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