Xanthine (XAB) Aptamer Details
ID# 7511
Structure
Chemistry
RNA
Target
Xanthine
Category
Small Organic
Affinity (Kd)
3.3 nM
Length
32
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprCprAprCprGprUprGprUprAprUprUprAprCprCprCprUprAprGprUprGprGprUprCprGprAprCprGprUprGprCprCp-3'
Molecular Weight: 10232.17
Extinction Coefficient: 307700
Binding Conditions / Buffer
Binding Buffer (20 mM Trisƒ??HCl (pH 7.5), 0.3 M NaCl and 5 mM MgCl2)
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Kiga, D., et al. "An RNA aptamer to the xanthine/guanine base with a distinctive mode of purine recognition." Nucleic Acids Research, 26 (1998): 1755-1760.
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