VEGF-Stimulated HUVECs Aptamer Details

ID# 7720

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Structure

Chemistry

Peptide

Target

VEGF-Stimulated human umbilical vein endothelial cells (HUVECs)

Sequence (3-char table code)

G A C U/T

5'-AspArgTrpArgProAlaLeuProValValLeuPheProLeuHis-3'

Molecular Weight: 2006.41

Extinction Coefficient:

Binding Conditions / Buffer

In vivo mice.

Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Asai et al. "Isolation of a Novel Peptide Homing to Tumor-Derived Neovasculature That Suppresses Tumor Growth." Biological Pharmaceutical Bulletin, 25(2002): 904-906.

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