Aptagen

VEGF receptor KDR/Flk-1 (K237) Aptamer Details

ID# 7629
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Structure
VEGF receptor KDR/Flk-1 (K237) structure
Chemistry
Peptide
Target
VEGF receptor KDR/Flk-1
Category
Protein
Affinity (Kd)
N/A nM
Length
12
Aptazyme
No

Sequence (3-char table code)

G A C U/T
NH2-HisThrMetTyrTyrHisHisTyrGlnHisHisLeu-COOH
Molecular Weight: 1803.06
Extinction Coefficient:

Binding Conditions / Buffer

Washing Buffer: 0.9% NaCl, 0.01 M phosphate buffer, pH 6.2, blocked with 0.3% BSA, 25 mM HEPES (pH 7.6) for 3 h.
Binding Temp: RT°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Hetian et al. "A novel peptide isolated from a phage display library inhibits tumor growth and metastasis by blocking the binding of vascular endothelial growth factor to its kinase domain receptor." J Biol Chem., 277(2002): 43137-42.
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