Aptagen

VEGF receptor KDR and Flt-1 (v107) Aptamer Details

ID# 7631
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Structure
VEGF receptor KDR and Flt-1 (v107) structure
Chemistry
Peptide
Target
VEGF receptor KDR and Flt-1
Category
Cells
Affinity (Kd)
0.6 µM
Length
19
Aptazyme
No

Sequence (3-char table code)

G A C U/T
NH2-GlyGlyAsnGluCysAspAlaIleArgMetTrpGluTrpGluCysPheGluArgLeu-COOH
Molecular Weight: 2606.94
Extinction Coefficient:

Binding Conditions / Buffer

Binding Buffer (0.5% (v/v) Tween20, 0.5% BSA in PBS)
Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Pan et al. "Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor." J Mol Biol, 316(2002): 769-787.
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