VEGF-KDR Aptamer Details
ID# 7624
Structure
Chemistry
Peptide
Target
VEGF-KDR
Category
Tissue
Affinity (Kd)
~80 µM
Length
7
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
NH2-AlaThrTrpLeuProProArg-COOH
Molecular Weight: 886.11
Extinction Coefficient:
Binding Conditions / Buffer
Binding Buffer: DMEM supplemented with 20 mM HEPES (pH 7.4) and 2 mg/mL gelatin
Binding Temp: 4°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Binetruy-Tournaire et al. "Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis." The EMBO Journal, 19(2000): 1525-1533.
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