Aptagen

VEGF-GlyApt-1 Aptamer Details

ID# 9277
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Structure
VEGF-GlyApt-1 structure
Chemistry
DNA
Target
Glycosylated VEGF peptide
Category
Peptide
Affinity (Kd)
2.5 ± 0.4 µM
Length
40
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dGpdCpdApdCpdCpdCpdTpdApdApdTpdGpdTpdGpdCpdApdApdGpdCpdTpdApdApdTpdGpdCpdGpdGpdApdApdTpdGpdGpdGpdGpdTpdCpdGpdGpdTpdTpdTpdTp-3'
Molecular Weight: 24,718 Da
Extinction Coefficient:

Binding Conditions / Buffer

Deionized water (incubation), TGK buffer for separation (25 mM Tris, 192 mM glycine, 5 mM KH₂PO₄)
Binding Temp: 25°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Selection of aptamers targeting small molecules by capillary electrophoresis: Advances, challenges, and prospects Y Hu, G Jiang, Y Wen, Y Shao, G Yang, F Qu - Biotechnology Advances, 2024 Aptamers, as novel recognition molecules, hold immense potential across various domains such as biosensing, nucleic acid drugs
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