Aptagen

VEGF (3R02 bivalent) Aptamer Details

ID# 7857
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Structure
VEGF (3R02 bivalent) structure
Chemistry
DNA
Target
Vascular Endothelial Growth Factor (VEGF)
Category
Protein
Affinity (Kd)
30 pM
Length
60
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dTpdGpdTpdGpdGpdGpdGpdGpdTpdGpdGpdApdCpdTpdGpdGpdGpdTpdGpdGpdGpdTpdApdCpdCpdTpdTpdTpdTpdTpdTpdTpdTpdTpdTpdTpdGpdTpdGpdGpdGpdGpdGpdTpdGpdGpdApdCpdTpdGpdGpdGpdTpdGpdGpdGpdTpdApdCpdCp-3'
Molecular Weight: 18836.24
Extinction Coefficient: 560300

Binding Conditions / Buffer

Binding buffer: 10 mM Tris-HCl, 100 mM NaCl, and 5 mM KCl (pH 7.4)
Binding Temp: 20°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Nonaka, Y. "Affinity Improvement of a VEGF Aptamer by in Silico Maturation for a Sensitive VEGF-Detection System." Anal. Chem., 85 (2013): 1132-1137.
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