Vascular Permeability Factor/Vascular Endothelial Growth Factor (NX-213) Aptamer Details
ID# 7547
Structure
Chemistry
Chimeric
Target
Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF)
Category
Protein
Affinity (Kd)
140 pM
Length
32
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dTsdTsdTsdTsmApnCpnCpnCpnUprGprApnUpmGprGpnUpmApmGprApnCpmGpnCpnCpmGpmGpmGpmGpnUpmGpdTsdTsdTsdTs-3'
Molecular Weight: 16446.5
Extinction Coefficient: 300400
Binding Conditions / Buffer
Selection Buffer (PBS: 10.1 mM Na2HPO4, 1.8 mM KH2PO4, 137 mM NaCl and 2.7 mM KCl (pH 7.4)) with 0.01 % human serum albumin
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Green L, Jellinek D, Janjic N, et al. (1995) "Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor." Chem Biol. 2:683-695.
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