UHA-2 Aptamer against Influenza A Viruses Aptamer Details
ID# 8739
Structure
Chemistry
DNA
Target
Hemagglutinin (HA) from Influenza A
Category
Protein
Affinity (Kd)
1.5 nM
Length
60
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dTpdApdGpdApdTpdTpdGpdGpdCpdCpdTpdTpdGpdCpdTpdApdTpdCpdApdCpdCpdCpdApdApdApdApdCpdCpdGpdTpdTpdTpdApdApdApdGpdCpdTpdGpdApdCpdCpdApdCpdGpdTpdGpdApdCpdGpdCpdTpdTpdCpdApdTpdCpdCpdGpdTp
Molecular Weight: 18329.9 g/mole
Extinction Coefficient: 560500
Binding Conditions / Buffer
20 mM Hepes, 150 mM NaCl, 2 mM KCl, 2 mM MgCl2, 2 mM CaCl2. 1 × washing buffer (pH 7.4)
Binding Temp: 23°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Meng Wang, Meng-Chan Hao, Yueyue Huangfu, Ke-Zhu Yang, Xiao-Qing Zhang, Yuan Zhang, Jianjun Chen, and Zhi-Ling Zhang. "A Universal Aptamer for Influenza A Viruses: Selection, Recognition, and Infection Inhibition." ACS Pharmacology & Translational Science 2024 7 (1), 249-258. DOI: 10.1021/acsptsci.3c00258
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