Tumour Marker MUC1 (S1.6) Aptamer Details
ID# 7491
Structure
Chemistry
DNA
Target
Tumour Marker MUC
Category
Peptide
Affinity (Kd)
0.2131 nM
Length
72
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdAp dGpdCpdApdApdCpdApdGpdGpdGpdTpdApdTpdCpdCpdApdApdApdGpdGpdApdTpdCpdApdApdApdTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp-3'
Molecular Weight: 22336.6
Extinction Coefficient: 737600
Binding Conditions / Buffer
Binding Buffer (0.2 M NaHCO3 and 0.5 M NaCl (pH 7.4))
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ferreira, C., et al. "DNA Aptamers That Bi nd to MUC1 Tumour Marker: Design and Characterization of MUC1-Binding Single-Stranded DNA Aptamers." Tumor Biology, 27(2006): 289ƒ??301.
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