Tumor Endothelial Cells (AraHH001) Aptamer Details

ID# 7856

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Structure

Chemistry

DNA

Target

Mouse and Human Tumour Endothelial Cells (mTECs and hTECs)

Sequence (3-char table code)

G A C U/T

5'-dApdCpdGpdTpdApdCpdCpdGpdApdCpdTpdTpdCpdGpdTpdApdTpdGpdCpdCpdApdApdCpdApdGpdCpdCpdCpdTpdTpdTpdApdTpdCpdCpdApdCpdCpdTpdCp-3'

Molecular Weight: 12071.86

Extinction Coefficient: 364700

Binding Conditions / Buffer

Selection Buffer: 50 mM Tris-HCl (pH 7.5), 5 mM KCl, 100 mM NaCl, 1 mM MgCl2, 250 mM sucrose and 0.1% sodium azide.

Binding Temp: 4°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Ara N, Hyodo M, Ohga N, Hida, N, Harishima H. (2012) Development of a novel DNA aptamer ligand targeting to primary cultured tumor endothelial cells by a cell-based SELEX method. PLOS one 7: e50174.

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