Aptagen

Tumor-derived endothelial cells (tRRL) Aptamer Details

ID# 7749
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Structure
Tumor-derived endothelial cells (tRRL) structure
Chemistry
Peptide
Target
Tumor-derived endothelial cells (TDECs)
Category
Cells
Affinity (Kd)
N/A nM
Length
10
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-TyrCysGlyGlyArgArgLeuGlyGlyCys-3'
Molecular Weight: 1141.4
Extinction Coefficient:

Binding Conditions / Buffer

PBS was used for Flow Cytometry assays. For radiometric binding assays, cell media varied according to cell line. See ref. for details.
Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

X Lu et al. Use of radioiodinated peptide arg-arg-leu targeted to neovascualrization as well as tumor cells in molecular tumor imaging. Chin J Cancer Res 24(2012): 52-59.
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