Aptagen

Tryptophan-Cp*Rh(III) sensor Aptamer Details

ID# 8050
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Structure
Tryptophan-Cp*Rh(III) sensor structure
Chemistry
DNA
Target
Tryptophan
Category
Small Organic
Affinity (Kd)
1.2 µM
Length
51
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dCpdTpdCpdTpdCpdGpdGpdGpdApdCpdGpdApdCpdCpdGpdCpdGpdGpdTpdApdGpdTpdCpdTpdTpdApdApdCpdCpdTpdApdApdApdGpdCpdGpdGpdTpdGpdTpdCpdApdGpdGpdTpdCpdGpdTpdCpdCpdCp-3'
Molecular Weight: 15668.16
Extinction Coefficient: 522150

Binding Conditions / Buffer

100 μM concentration of monomeric Cp*Rh(III)
Binding Temp: 24 °C°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058
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