Triple-negative breast cancer MDA-MB-231 aptamer (Apt2) Aptamer Details

ID# 8538

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Structure

Chemistry

DNA

Target

Human triple-negative breast cancer cell line MDA-MB-231

Sequence (3-char table code)

G A C U/T

5'-dGpdCpdCpdTpdGpdTpdTpdGpdTpdGpdTpdCpdCpdTpdApdApdCpdApdTpdGpdTpdTpdGpdTpdTpdGpdCpdCpdGpdGpdGpdApdCpdGpdCpdCpdTpdCpdCpdTpdTpdCpdApdCpdCpdApdApdApdGpdTpdTpdGpdGpdTpdGpdTpdCpdCpdCpdCpdApdCpdCpdTpdApdCpdCpdApdTpdGpdCpdTpdTpdApdTpdTpdCpdTpdTpdGpdTpdCpdTpdCpdCpdCp-3'

Molecular Weight: 27417.7

Extinction Coefficient:

Binding Conditions / Buffer

1 mM CaCl2·2H2O and 1.5 mM MgCl2·6H2O in 1X PBS, pH 7.4

Binding Temp: 37 °C°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Ferreira D, Barbosa J, Sousa DA et al. Selection of aptamers against triple negative breast cancer cells using high throughput sequencing. Sci Rep 11, 8614 (2021). https://doi.org/10.1038/s41598-021-87998-y

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