Aptagen

Tr-8 Aptamer Details

ID# 8036
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Structure
Tr-8 structure
Chemistry
RNA
Target
CD25
Category
Protein
Affinity (Kd)
35.7 nM
Length
51
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-rGprGprGprAprGprGprAprCprGprAprUprGprCprGprGprGprCprCprGprUprUprGprUprUprGprUprGprUprGprCprCprGprCprCprCprCprAprGprAprCprGprAprCprUprCprGprCprCprCprGprAp-3'
Molecular Weight: 13869.47
Extinction Coefficient: 605800

Binding Conditions / Buffer

HEPES-buffered saline, pH=7.5 with 2mmol/L CaCl2
Binding Temp: 37°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Veeramani, Suresh,et al."An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients" American Association for Cancer Research 7, (2019) 1511-1522
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