Tr-1 Aptamer Details
ID# 8037
Structure
Chemistry
RNA
Target
IL2-CD25 Complex
Category
Protein
Affinity (Kd)
67.8 nM
Length
51
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprAprGprGprAprCprGprAprUprGprCprGprGprUprCprCprUprGprUprCprGprUprCprUprGprUprUprCprGprUprCprCprCprCprAprGprAprCprGprAprCprUprCprGprCprCprCprGprAp-3'
Molecular Weight: 13299.14
Extinction Coefficient: 593700
Binding Conditions / Buffer
HEPES-buffered saline, pH=7.5 with 2mmol/L CaCl2
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Veeramani, Suresh,et al."An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients" American Association for Cancer Research 7, (2019) 1511-1522
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