TLR3-ECD (Family-1) Aptamer Details
ID# 7606
Structure
Chemistry
RNA
Target
Toll-like receptor 3 Ectodomain
Category
Protein
Affinity (Kd)
2.1 nM
Length
64
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprUprAprGprAprUprAprCprGprAprUprGprGprAprUprAprCprCprCprCprCprUprGprUprGprGprCprCprCprGprUprCprAprAprCprAprCprAprGprGprGprGprAprAprGprUprGprGprCprAprUprGprAprCprGprCprGprCprAprGprCprCprAp-3'
Molecular Weight: 20703.58
Extinction Coefficient: 628900
Binding Conditions / Buffer
Binding buffer: 2 mM HEPES-NaOH (pH 7.6), 3 mM MgCl2, and 100 mM NaCl
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Watanabe et al. "Isolation of RNA aptamers against human Toll-like receptor 3 ectodomain." Nucleic Acids Symposium Series No. 50 (2006): 251-252.
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