Aptagen

Thrombopoietin Receptor (AF12505) Aptamer Details

ID# 7661
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Structure
Thrombopoietin Receptor (AF12505) structure
Chemistry
Peptide
Target
Thrombopoietin Receptor
Category
Protein
Affinity (Kd)
2 nM
Length
14
Aptazyme
No

Sequence (3-char table code)

G A C U/T
NH2-IleGluGlyProThrLeuArgGlnTrpLeuAlaAlaArgAla-COOH
Molecular Weight: 1754.06
Extinction Coefficient:

Binding Conditions / Buffer

Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Cwirla et al. "Peptide Agonist of the Thrombopoietin Receptor as Potent as the Natural Cytokine." Science, 276(1997): 1696-1699.
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