Aptagen

Thiol-modified thrombin Aptamer Aptamer Details

ID# 8159
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Structure
Thiol-modified thrombin Aptamer structure
Chemistry
DNA
Target
Thrombin
Category
Protein
Affinity (Kd)
0.3 fM
Length
15
Aptazyme
No

Sequence (3-char table code)

G A C U/T
SH-(CH2)6-dGpdGpdTpdTpdGpdGpdTpdGpdTpdGpdGpdTpdTpdGpdGp
Molecular Weight: 5039.41
Extinction Coefficient: 142641

Binding Conditions / Buffer

0.1 M Na2HPO4, 0.1 M KH2PO4 and 0.1 M NaCl. 20 mM Tris–HCl buffer (pH 7.4) containing 140 mM NaCl, 5 mM KCl and 1 mM MgCl2
Binding Temp: 25°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

doi:10.1016/j.aca.2013.09.060
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