TGF-??1 (T18_1_3) Aptamer Details
ID# 7475
Structure
Chemistry
DNA
Target
Transforming Growth Factor-??1 (TGF-??1)
Category
Protein
Affinity (Kd)
94 nM
Length
74
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdGpdCpdTpdCpdGpdGpdCpdTpdTpdCpdApdCpdGpdApdGpdApdTpdTpdCpdGpdTpdGpdTpdCsdGpdTpdTpdGpdTpdGpdTpdCsdCsdTpdGpdTpdAsdCsdCsdCsdGpdCsdCsdTpdTpdGpdAsdCsdCsdAsdGpdTpdCsdAsdCsdTpdCsdTpdAsdGpdAsdGpdCsdAsdTpdCsdCsdGpdGpdAsdCsdTpdGp-3'
Molecular Weight: 23064.62
Extinction Coefficient: 673000
Binding Conditions / Buffer
PBS with 1 MgCl2.
Binding Temp: RT°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Kang, Jonghoon, et al. "Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-??1 protein." Bioorganic & Medicinal Chemistry Letters, 18 (2008): 1835-1839.
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