Tetrodotoxin (TTX)-binding Phosphorothioate (PS) Aptamer Aptamer Details
ID# 10141
Structure
Chemistry
DNA
Target
Tetrodotoxin (TTX)
Category
Small Organic
Affinity (Kd)
14.3 µM
Length
30 Base Pairs
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdApdApdApdApdTpdTpdTpdCpdApdCpdApdCpdGpdGpdGpdTpdGpdCpdCpdTpdCpdGpdGpdCpdTpdGpdTpdCpdCp
Molecular Weight: 9167 g/mole
Extinction Coefficient: 28
Binding Conditions / Buffer
1x Phosphate Buffered Saline (PBS)(154 mM NaCl, 5.6 mM Na2HPO4, 1.1 mM KH2PO4, pH 7.4)
Binding Temp: 25 °C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wang, D., Li, Y., Deng, X. et al. An aptamer-based depot system for sustained release of small molecule therapeutics. Nat Commun 14, 2444 (2023). https://doi.org/10.1038/s41467-023-37002-0
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