Tb-1 Aptamer Details
ID# 9779
Structure
Chemistry
DNA
Target
Trivalent lanthanide ions
Category
Other
Affinity (Kd)
3.9 nM
Length
42
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
Molecular Weight: 13115.5 g/mole
Extinction Coefficient: 422300
Binding Conditions / Buffer
10 mM MES, pH 6.0, 100 mM NaCl, 2 mM MgCl2
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wang, J., Wang, X., Li, X., Li, X., Lei, H., & Liu, J. (2025). A DNA aptamer for trivalent lanthanide ions with low nanomolar affinity. Inorganic Chemistry Frontiers. https://doi.org/10.1039/d5qi00391a
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