Aptagen

T3 Aptamer Details

ID# 8186
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Structure
T3 structure
Chemistry
DNA
Target
Ovarian cancer tumor cells
Category
Tissue
Affinity (Kd)
PBS with 5 mM MgCl2
Length
75
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dCsdGsdCsdTsdCsdGsdGsdAsdTsdCsdGsdAsdTsdAsdAsdGsdCsdTsdTsdCsdGsdAsdGsdCsdCsdTsdGsdAsdGsdTsdTsdTsdTsdTsdGsdCsdCsdGsdCsdGsdAsdTsdCsdTsdCsdGsdAsdCsdCsdTsdCsdCsdGsdTsdCsdAsdCsdGsdGsdAsdTsdCsdCsdTsdCsdTsdAsdGsdAsdGsdCsdAsdCsdTsdGs-3'
Molecular Weight: 22910.14
Extinction Coefficient: 679131

Binding Conditions / Buffer

37°C
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Wang, Hongyu et al. “Morph-X-Select: Morphology-based tissue aptamer selection for ovarian cancer biomarker discovery.” BioTechniques vol. 61,5 249-259. 1 Nov. 2016, doi:10.2144/000114473
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