T-2 Aptamer Details
ID# 8098
Structure
Chemistry
DNA
Target
thyroglobulin
Category
Protein
Affinity (Kd)
3.18 nM
Length
40
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5’-dCpdGpdCpdGpdTpdGpdApdGpdCpdGpdGpdGpdGpdApdGpdGpdCpdGpdApdTpdGpdCpdCpdCpdApdGpdGpdCpdTpdApdApdCpdTpdTpdGpdApdCpdTpdCpdAp -3’
Molecular Weight: 12388
Extinction Coefficient: 380500
Binding Conditions / Buffer
TGK, Tris-HCl, BBS, and PBS
Binding Temp: 22°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Zhu, C., Li, L., Fang, S., Zhao, Y., Zhao, L., Yang, G., & Qu, F. (2020). Selection and Characterization of an ssDNA Aptamer against Thyroglobulin. Talanta, 121690. doi:10.1016/j.talanta.2020.121690
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