Aptagen

Staphylococcus aureus ClfA (4503‐73) Aptamer Details

ID# 10025
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Structure
Staphylococcus aureus ClfA (4503‐73) structure
Chemistry
DNA
Target
Clumping Factor A protein of Staphylococcus aureus (S. aureus) NRS384 (USA300)
Category
Protein
Affinity (Kd)
0.79 nM
Length
40
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dApdTpdCpdTpdCpdCpdTpdTpdCpdApdApdApdGpdTpdGpdGpdCpdGpdApdTpdTpdGpdGpdGpdCpdApdTpdCpdTpdGpdGpdTpdTpdTpdTpdTpdApdApdGpdTp-3'
Molecular Weight: 12403.1 g/mole
Extinction Coefficient: 384000

Binding Conditions / Buffer

SB18T buffer (40 mM HEPES pH 7.5, 0.1 M NaCl, 5 mM KCl, 5 mM MgCl2 and 0.05% Tween‐20)
Binding Temp: Room Temperature°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Baumstummler A, Lehmann D, Janjic N, Ochsner UA. Specific capture and detection of Staphylococcus aureus with high-affinity modified aptamers to cell surface components. Lett Appl Microbiol. 2014 Oct;59(4):422-31. doi: 10.1111/lam.12295. Epub 2014 Jul 2. PMID: 24935714; PMCID: PMC4299505.
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