SQ-2 Aptamer Details
ID# 8066
Structure
Chemistry
RNA
Target
ALPPL-2
Category
Protein
Affinity (Kd)
22.25-24.74 nM
Length
76
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rAprUprAprCprCprAprGprCprUprUprAprUprUprCprAprAprUprUprGprCprCprUprGprAprAprAprAprGprCprUprAprUprCprGprCprCprCprAprAp rUprUprCprGprCprAprGprUprGprAprUprAprUprCprCprUprUprUprAprAprGprAprUprAprGprUprAprAprGprUprGprCprAprAprUprCprUp-3'
Molecular Weight: 22995.6
Extinction Coefficient: 711400
Binding Conditions / Buffer
4.5 g/L glucose, 5 mmol/L MgCl2, 0.1 mg/mL yeast tRNA, and 1 mg/mL bovine serum albumin (BSA) in Dulbecco's PBS
Binding Temp: 4°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Dua, P., Kang, H. S., Hong, S.-M., Tsao, M.-S., Kim, S., & Lee, D. -k. (2013). Alkaline Phosphatase ALPPL-2 Is a Novel Pancreatic Carcinoma-Associated Protein. Cancer Research, 73(6), 1934–1945. doi:10.1158/0008-5472.can-12-3682
Request a Quote
Have your aptamer oligo synthesized by Aptagen.
