spl3c Aptamer Details
ID# 8661
Structure
Chemistry
DNA
Target
Human bladder Carcinoma
Category
Small Organic
Affinity (Kd)
79 nM
Length
49
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dApdGpdCpdCpdCpdTpdCpdGpdGpdGpdApdTpdTpdApdTpdCpdGpdGpdTpdGpdTpdTpdTpdApdTpdGpdGpdTpdGpdTpdCpdTpdGpdTpdCpdTpdApdTpdCpdApdCpdGpdTpdGpdGpdApdGpdCpdTp
Molecular Weight: 15131.8
Extinction Coefficient:
Binding Conditions / Buffer
4
Binding Temp: 4°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
J. Am. Chem. Soc. 2024, 146, 1, 319–329
Publication Date:December 21, 2023
https://doi.org/10.1021/jacs.3c09091
Copyright © 2023 American Chemical Society
Wang, X., Zhang, L., Qiu, S., Wang, X., Liu, H., & Chen, T. (2022). Elucidation of CKAP4-remodeled cell mechanics in driving metastasis of bladder cancer through aptamer-based target discovery. Proceedings of the National Academy of Sciences, 119(16), e2110500119. https://doi.org/10.1073/pnas.2110500119
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