SP3 Aptamer Details
ID# 8112
Structure
Chemistry
DNA
Target
Sepiapterin reductase deficiency (SR)
Category
Other
Affinity (Kd)
37.3 nM
Length
59
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdApdGpdGpdApdTpdGpdApdCpdTpdGpdApdCpdGpdApdCpdGpdApdTpdGpdGpdGpdApdApdTpdGpdGpdApdGpdApdGpdGpdApdApdGpdGpdGpdGpdApdTpdApdTpdApdGpdGpdTpdApdTpdGpdTpdTpdGpdGpdApdTpdGpdTpdApdGp-3'
Molecular Weight: 18637.1
Extinction Coefficient: 623400
Binding Conditions / Buffer
50 mM Tris, pH 7.5, 150 mM NaCl and 2 mM MgCl2
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Eissa S, Alkhaldi S, Chinnappan R, Siddiqua A, Abduljabbar M, Abdel Rahman AM, Dasouki M, Zourob M. Selection, characterization, and electrochemical biosensing application of DNA aptamers for sepiapterin. Talanta. 2020 Aug 15;216:120951. doi: 10.1016/j.talanta.2020.120951. Epub 2020 Mar 20. PMID: 32456943.
Request a Quote
Have your aptamer oligo synthesized by Aptagen.
