Sialyl Lewis X (5) Aptamer Details
ID# 7465
Structure
Chemistry
RNA
Target
Sialyl Lewis X
Category
Other
Affinity (Kd)
0.085 nM
Length
133
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rCprCprGprUprAprAprUprAprCprGprAprCprUprCprAprCprUprAprUprAprGprGprGprGprAprGprCprUprCprGprGprUprAprCprCprGprAprAprUprUprCprAprAprGprGprUprAprCprUprCprUprGprUprGprCprUprUprGprUprCprGprAprUprGprUprGprUprAprUprUprGprAprUprGprGprCprAprCprUprUprUprCprGprAprGprUprCprAprAprCprGprAprGprUprUprGprAprCprAprGprAprAprCprAprAprGprUprAprGprUprCprAprAprGprCprUprUprUprGprCprAprGprAprGprAprGprGprAprUprCprCprUprUp-3'
Molecular Weight: 42804.72
Extinction Coefficient: 1336400
Binding Conditions / Buffer
Binding Buffer (150 mM NaCl, 20 mM Hepes (pH 7.4), 1 mM CaCl2, 1 mM MgCl2)
Binding Temp: RT°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Jeong, Sunjoo, et al. "In Vitro Selection of the RNA Aptamer against the Sialyl Lewis X and Its Inhibition of the Cell Adhesion." Biochemical and Biophysical Research Communications, 281 (2001): 237ƒ??243.
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