Seq-2 Aptamer Details
ID# 8189
Structure
Chemistry
DNA
Target
Unknown tumor marker - colorectal cancer
Category
Protein
Affinity (Kd)
11.31 nM
Length
88
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdTpdApdTpdApdGpdCpdApdApdTpdGpdGpdTpdApdCpdGpdGpdTpdApdCpdTpdTpdCpdCpdTpdApdApdCpdTpdCpdGpdTpdCpdCpdCpdTpdApdCpdCpdGpdApdGpdCpdCpdTpdCpdTpdCpdTpdCpdTpdGpdGpdTpdCpdCpdTpdTpdGpdCpdApdApdCpdTpdCpdApdApdApdApdGpdTpdGpdCpdApdCpdGpdCpdTpdApdCpdTpdTpdTpdGpdCpdTpdApdAp-3'
Molecular Weight: 26842.4
Extinction Coefficient: 810200
Binding Conditions / Buffer
1X PBS solution at a pH of 7.4 incubated at 37°C for 1 hour.
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Li, K., Qi, L., Gao, L. M., Shi, M., Li, J., Liu, Z. W., & Zhao, L. (2019). Selection and preliminary application of a single stranded DNA aptamer targeting colorectal cancer serum. RSC Advances, 9(66), 38867–38876. https://doi.org/10.1039/c9ra04777h
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