Saxitoxin (Apt STX1) Aptamer Details
ID# 10053
Structure
Chemistry
DNA
Target
Saxitoxin
Category
Small Organic
Affinity (Kd)
10 mM phosphate buffer, 2.7 mM KCl, 140 mM NaCl, 0.05% Tween-20, pH 7.4
Length
78
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdTpdApdTpdTpdGpdApdGpdGpdGpdTpdCpdGpdCpdApdTpdCpdCpdCpdGpdTpdGpdGpdApdApdApdCpdApdTpdGpdTpdTpdCpdApdTpdTpdGpdGpdGpdCpdGpdCpdApdCpdTpdCpdCpdGpdCpdTpdTpdTpdCpdTpdGpdTpdApdGpdApdTpdGpdGpdCpdTpdCpdTpdApdApdCpdTpdCpdTpdCpdCpdTpdCpdTp-3'
Molecular Weight: 23967.5 g/mole
Extinction Coefficient: 716400
Binding Conditions / Buffer
24°C
Binding Temp: 95°C for 5 minutes and then left to cool on ice for at least 10 minutes
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Sara M. Handy, Betsy Jean Yakes, Jeffrey A. DeGrasse, Katrina Campbell, Christopher T. Elliott, Kelsey M. Kanyuck, Stacey L. DeGrasse, First report of the use of a saxitoxin–protein conjugate to develop a DNA aptamer to a small molecule toxin,
Toxicon, Volume 61, 2013, Pages 30-37, ISSN 0041-0101,
https://doi.org/10.1016/j.toxicon.2012.10.015.
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