SARS-CoV-2 Aptamer 1C – Apta-switch antisense Aptamer Details

ID# 8041

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Structure

Chemistry

DNA

Target

RBD of the Spike glycoprotein from SARS-CoV-2

Sequence (3-char table code)

G A C U/T

5'-dTpdGpdTpdCpdCpdApdTpdTpdApdApdCpdGpdCpdCpdCp-3'

Molecular Weight: 15

Extinction Coefficient:

Binding Conditions / Buffer

10 mM Tris, 0.5 mM NaCl, 1 mM EDTA, pH 7.4

Binding Temp: 23°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Singh NK, Ray P, Carlin AF, Magallanes C, Morgan SC, Laurent LC, Aronoff-Spencer ES, Hall DA. "Hitting the diagnostic sweet spot: Pont-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf gluocometer". medRxiv preprint. doi: https://doi.org/10.1101/2020.09.24.20200394.

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