SARS-CoV-2 Aptamer 1C Aptamer Details

ID# 8006

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Structure

Chemistry

DNA

Target

RBD of the Spike glycoprotein from SARS-CoV-2

Sequence (3-char table code)

G A C U/T

5’-dCpdApdGpdCpdApdCpdCpdGpdApdCpdCpdTpdTpdGpdTpdGpdCpdTpdTpdTpdGpdGpdGpdApdGpdTpdGpdCpdTpdGpdGpdTpdCpdCpdApdApdGpdGpdGpdCpdGpdTpdTpdApdApdTpdGpdGpdApdCpdAp-3’

Molecular Weight: 15787.2

Extinction Coefficient: 482900

Binding Conditions / Buffer

PBS

Binding Temp: 95C->4C->25C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Song, Yanling; Song, Jia; Wei, Xinyu; Huang, Mengjiao; Sun, Miao; Zhu, Lin; et al. (2020): Discovery of Aptamers Targeting Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein. ChemRxiv. Preprint. https://doi.org/10.26434/chemrxiv.12053535.v2 Song, Y., Song, J., Wei, X., Huang, M., Sun, M., Zhu, L., Lin, B., Shen, H., Zhu, Z., and C. Yang. 2020. Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV‑2 Spike Glycoprotein. Analytical Chemistry 2020, 92, 9895−9900. https://dx.doi.org/10.1021/acs.analchem.0c01394

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