S3-2-3 Aptamer Details
ID# 8178
Structure
Chemistry
DNA
Target
Esophageal cancer cells.
Category
Cells
Affinity (Kd)
265 nM
Length
18
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdTpdGpdGpdCpdCpdApdGpdGpdGpdGpdGpdGpdApdGpdGpdGpdGp-3'
Molecular Weight: 5710.7
Extinction Coefficient: 184000
Binding Conditions / Buffer
4.5 g L−1 glucose, 5 mM MgCl2, 1 mg mL−1 bovine serum albumin (BSA) and 0.1 mg mL−1 yeast tRNA in 0.01 M PBS
Binding Temp: 4°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Chen, X., Zhang, Y., Shi, Y., Niu, T., Li, B., & Guo, L. et al. (2021). Evolution of DNA aptamers against esophageal squamous cell carcinoma using cell-SELEX. The Analyst, 146(13), 4180-4187. doi: 10.1039/d1an00634g
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