S2.2 Aptamer Details
ID# 7974
Structure
Chemistry
DNA
Target
MUC1
Category
Protein
Affinity (Kd)
0.135 nM
Length
25
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdCpdApdGpdTpdTpdGpdApdTpdCpdCpdTpdTpdTpdGpdGpdApdTpdApdCpdCpdCpdTpdGpdGp-3'
Molecular Weight: 7664.03
Extinction Coefficient: 232300
Binding Conditions / Buffer
PBS buffer (pH 7.2); Room Temperature (overnight)
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
D Seleci et al. Aptamer mediated niosomal drug delivery. RSC Adv 6(2016): 87910-87918.
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