RIG-I (CL9) Aptamer Details

ID# 7610

Back to Search Results

Structure

Chemistry

2'-F-RNA

Target

RIG-I

Sequence (3-char table code)

G A C U/T

5'-rGprGprGprAprGprAprGpfCprGprGprAprAprGpfCprGpfUprGpfCpfUprGprGprGpfCpfCprApfCpfCprApfUpfCpfCprGpfUprAprApfCpfUprAprGpfCpfUprAprApfUprApfCpfUpfUprGpfUpfUprApfUpfCpfUpfUpfUpfUpfUprApfUpfUpfUpfUpfCprApfUprAprApfCpfCpfCprAprGprAprGprGpfUpfCprGprApfUprGprGprApfUpfCpfCpfCpfCpfCpfCp-3'

Molecular Weight: 29522.39

Extinction Coefficient: 900600

Binding Conditions / Buffer

1X PBS with 1 mM MgCl2

Binding Temp: 4°C

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Hwang et al. "5'-Triphosphate-RNA-independent activation of RIG-1 via RNA aptamer with enhanced antiviral activity." Nucleic Acids Research 40(2011): 2724 - 2733

Request a Quote Have your aptamer oligo synthesized by Aptagen.