Aptagen

RGD motifs in Fibronectin and Vitronectin Aptamer Details

ID# 7659
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Structure
RGD motifs in Fibronectin and Vitronectin structure
Chemistry
Peptide
Target
RGD motifs in Fibronectin and Vitronectin
Category
Protein
Affinity (Kd)
N/A nM
Length
8
Aptazyme
No

Sequence (3-char table code)

G A C U/T
NH2-CysTrpAspAspGlyTrpLeuCys-COOH
Molecular Weight: 1061.26
Extinction Coefficient:

Binding Conditions / Buffer

TBS Wash Buffer
Binding Temp:

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Pasqualini et al. "A Peptide Isolated from Phage Display Libraries Is a Structural and Functional Mimic of an RGD-binding Site on Integrins." The Journal of Cell Biology, 130(1995): 1189-1196.
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