Recombinant human bone morphogenetic protein 2 (rhBMP-2) (BA1) Aptamer Details

ID# 10136

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Structure

Chemistry

DNA

Target

rhBMP-2

Sequence (3-char table code)

G A C U/T

5'-dCpdGpdTpdApdCpdGpdGpdTpdCpdGpdApdCpdGpdCpdTpdApdGpdCpdApdApdApdApdCpdApdApdApdApdApdApdApdApdApdTpdApdApdApdApdApdApdApdApdApdApdApdGpdApdCpdTpdApdApdApdGpdApdCpdApdCpdGpdTpdGpdGpdApdGpdCpdTpdCpdGpdGpdApdTpdCpdCp-3'

Molecular Weight: 21991.4 g/mole

Extinction Coefficient: 741200

Binding Conditions / Buffer

20 mM HEPES, 2 mM MgCl2, 2 mM CaCl2, 2 mM KCl, 150 mM NaCl, pH 7.4, 0.05% Tween-20

Binding Temp: Room Temperature°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Liu, M.; Kinghorn, A.B.; Wang, L.; Bhuyan, S.K.; Shiu, S.C.-C.; Tanner, J.A. The Evolution and Application of a Novel DNA Aptamer Targeting Bone Morphogenetic Protein 2 for Bone Regeneration. Molecules 2024, 29, 1243. https://doi.org/10.3390/molecules29061243

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