R8-1 (5′) Aptamer Details

ID# 9676

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Structure

Chemistry

DNA

Target

MC1-R (Melanocortin Receptor 1)

Sequence (3-char table code)

G A C U/T

dApdGpdCpdApdGpdCpdApdCpdApdGpdApdGpdGpdTpdCpdApdGpdApdTpdGpdTpdGpdCpdTpdGpdGpdTpdTpdGpdCpdGpdGpdApdCpdGpdTpdGpdApdApdCpdApdApdApdTpdGpdTpdTpdApdApdCpdCpdGpdApdApdCpdTpdGpdTpdTpdGpdTpdTpdCpdApdCpdGpdGpdTpdApdGpdCpdApdCpdGpdCpdApdTpdApdGpdGp

Molecular Weight: 24857.1 g/mole

Extinction Coefficient: 789100

Binding Conditions / Buffer

Binding buffer (20 mM Tris-HCl, 100 mM NaCl, 1 mM MgCl2, pH = 7.0). This buffer was used to immobilize the library onto the magnetic beads.

Binding Temp: 25°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

He, Y., Shang, Z., Pei, X., & Yang, X. (2025). Capture-SELEX screening for a new nanomolar affinity aptamers for label-free detection of human MC1-R and applications potential in cosmetics. Microchemical Journal, 219, 115931. https://doi.org/10.1016/j.microc.2025.115931

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