R10A4 Aptamer Details
ID# 9612
Structure
Chemistry
DNA
Target
Adenine
Category
Other
Affinity (Kd)
1 µM
Length
42
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dGpdApdCpdGpdApdCpdGpdGpdGpdTpdTpdTpdTpdTpdGpdTpdTpdApdGpdApdApdApdApdGpdTpdTpdCpdTpdGpdGpdTpdGpdGpdTpdGpdGpdTpdApdApdGpdTpdCpdGpdTpdCp
Molecular Weight: 12945.4
Extinction Coefficient: 403600
Binding Conditions / Buffer
25°C
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ding Y, Gu L, Wang X, Zhang Z, Zhang H, Liu J. Affinity-Guided Coevolution of Aptamers for Guanine, Xanthine, Hypoxanthine, and Adenine. ACS Chem Biol. 2024 Jan 19;19(1):208-216. doi: 10.1021/acschembio.3c00660. Epub 2024 Jan 9. PMID: 38194356.
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