Protein Kinase R (PKR) Aptamer Aptamer Details

ID# 8744

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Structure

Chemistry

RNA

Target

Protein Kinase R (PKR)

Sequence (3-char table code)

G A C U/T

rAprCprGprUprAprCprGprUprAprCprGprUprAprCprGprUp

Molecular Weight: 120120

Extinction Coefficient:

Binding Conditions / Buffer

Refolding Buffer: 333 mM HEPES, pH 8.0, 333 mM NaCl, 33 mM MgCl2. After refolding, incubate with 100 mM of 2-methylnicotinic acid imidazolide (NAI) in DMSO for 10 min at 37°C.

Binding Temp: 37°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Guo, SK., Liu, CX., Xu, YF. et al. Therapeutic application of circular RNA aptamers in a mouse model of psoriasis. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02204-4

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