Prostate-specific membrane antigen (xPSM-A9) Aptamer Details

ID# 10128

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Structure

Chemistry

2'-F-RNA

Target

Prostate-specific membrane antigen (PSMA)

Sequence (3-char table code)

G A C U/T

5'-rGprGprGprAprGprGprApfCprGprApfUprGpfCprGprGprApfCpfCpfCprGprAprAprAprAprAprGprApfCpfCpfUprGprApfCpfCpfUprGprApfCpfUpfUpfCpfUprApfUprApfCpfUprAprAprGpfUpfCpfUprAprAprGpfUpfCpfUprApfCprGpfUpfUpfCpfCpfCprAprGprApfCprGprApfCpfUpfCprGpfCpfCpfCprGprAp-3'

Molecular Weight: 21393.7 g/mole

Extinction Coefficient: 665700

Binding Conditions / Buffer

40mM Tris-HCL, pH = 7.4

Binding Temp: 37 °C °C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Shawn E. Lupold, Brian J. Hicke, Yun Lin, Donald S. Coffey; Identification and Characterization of Nuclease-stabilized RNA Molecules That Bind Human Prostate Cancer Cells via the Prostate-specific Membrane Antigen1. Cancer Res 15 July 2002; 62 (14): 4029–4033. http://www.ncbi.nlm.nih.gov/pubmed/12124337

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