Potassium (K-R17-36a) Aptamer Details

ID# 10021

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Structure

Chemistry

DNA

Target

Potassium ions

Sequence (3-char table code)

G A C U/T

5'-dApdCpdTpdGpdCpdCpdTpdGpdGpdTpdGpdTpdGpdGpdTpdTpdGpdGpdGpdTpdTpdTpdGpdGpdCpdGpdTpdGpdGpdCpdGpdGpdTp-3'

Molecular Weight: 10310.6 g/mole

Extinction Coefficient: 301600

Binding Conditions / Buffer

100 mM LiCl, 5 mM MgCl2, and 20 mM HEPES acid with pH adjusted to 7.4 using LiOH

Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Qing Zhao, Kaijun Chen, Shiyuan Liu, Juewen Liu, SELEX-derived potassium aptamers for robust detection in a physiological sodium background, Biosensors and Bioelectronics, Volume 310, 2026, 118881, ISSN 0956-5663, https://doi.org/10.1016/j.bios.2026.118881.

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