Plasminogen Activator Inhibitor-1 (PAI-1-01) Aptamer Details

ID# 10101

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Structure

Chemistry

DNA

Target

Plasminogen activator inhibitor-1

Sequence (3-char table code)

G A C U/T

5'-dApdGpdCpdApdGpdCpdApdCpdApdGpdApdGpdGpdTpdCpdApdGpdApdTpdGpdCpdApdTpdTpdGpdApdGpdApdTpdApdGpdCpdTpdApdGpdTpdTpdGpdTpdApdGpdCpdTpdGpdCpdGpdTpdCpdApdTpdApdGpdGpdCpdTpdGpdGpdGpdTpdTpdGpdGpdGpdTpdCpdTpdApdGpdTpdGpdGpdTpdTpdGpdGpdGpdTpdGpdTpdGpdCpdCpdTpdApdTpdGpdCpdGpdTpdGpdCpdTpdApdCpdCpdGp-3'

Molecular Weight: 31183.1 g/mole

Extinction Coefficient: 971500

Binding Conditions / Buffer

10 mM Tris pH 8.0, 50 mM NaCl, 1 mM EDTA

Binding Temp: Room temperature°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Wang, J., Gong, Q., Maheshwari, N., Eisenstein, M., Arcila, M.L., Kosik, K.S. and Soh, H.T. (2014), Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers†. Angew. Chem. Int. Ed., 53: 4796-4801. https://doi.org/10.1002/anie.201309334

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