NS13 Aptamer Details
ID# 8074
Structure
Chemistry
DNA
Target
N‑Cadherin Protein
Category
Protein
Affinity (Kd)
93 nM
Length
40
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'- dApdCpdTpdTpdGpdCpdTpdCpdTpdGpdApdTpdGpdCpdGpdApdCpdApdApdCpdCpdTpdTpdTpdTpdGpdCpdCpdCpdApdGpdApdTpdApdGpdTpdApdApdGpdTp -3'
Molecular Weight: 40
Extinction Coefficient: 378300
Binding Conditions / Buffer
1X PBS
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Yang, L., Gao, T., Li, W., Luo, Y., Ullah, S., Fang, X., … Pei, R. (2020). Ni-Nitrilotriacetic Acid Affinity SELEX Method for Selection of DNA Aptamers Specific to the N-Cadherin Protein. ACS Combinatorial Science. doi:10.1021/acscombsci.0c00165
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