NS-1 Aptamer Aptamer Details
ID# 7878
Structure
Chemistry
DNA
Target
Influenza A virus (IAV) non-stuctural protein (NS1)
Category
Protein
Affinity (Kd)
18.91 nM
Length
88
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dGpdCpdApdApdTpdGpdGpdTpdApdCpdGpdGpdTpdApdCpdTpdTpdCpdCpdGpdCpdGpdGpdTpdCpdCpdGpdGpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdTpdGpdGpdTpdGpdGpdGpdGpdGpdGpdTpdGpdCpdGpdGpdGpdGpdGpdGpdGpdCpdGpdGpdCpdCpdGpdCpdApdApdApdApdGpdTpdGpdCpdApdCpdGpdCpdTpdApdCpdTpdTpdTpdGpdCpdTpdApdAp
Molecular Weight: 27570.81
Extinction Coefficient: 834900
Binding Conditions / Buffer
50 mM Tris/Cl (pH 8.0), 150 mM NaCl, 1.5 mM MgCl2, 2 mM DTT and 1% (w/v) BSA
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Woo, H., Kim, K., Lee, J., Shim, H., Cho, S., Lee, W., Ko, H., Keum, Y., Kim, S., Pathinayake, P., Kim, C., and Jeong, Y. "Single-stranded DNA aptamer that specifically binds to the influenza virus NS1 protein suppresses interferon antagonism." Antiviral Research 100.2(2013): 337-345.
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