Neurotensin receptor NTS-1 (P19) Aptamer Details
ID# 7580
Structure
Chemistry
2'-F-RNA
Target
Neurotensin receptor NTS-1
Category
Protein
Affinity (Kd)
0.37 nM
Length
70
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprAprGprGprApfCprGprApfUprGpfCprGprGprApfCprAprGprApfUprApfCprGprGprAprApfCpfUprApfCprAprGprAprGprGpfUpfCprAprApfUpfUprApfCprGprGpfUprGprGpfCpfCprApfCprGpfCprAprGprApfCprGprApfCpfUpfCprGpfCpfCpfCprGprAp-3'
Molecular Weight: 22801.8
Extinction Coefficient: 701900
Binding Conditions / Buffer
Binding Buffer (SHMCK buffer containing 0.1% (w/v) HSA, 0.2% (w/v) CHAPS, 0.04% (w/v) CHS, and 0.1% (w/v) LM)
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Daniels et al. "Generation of RNA Aptamers to the G-Protein-Coupled Receptor for Neurotensin, NTS-1." Journal of Analytical Biochemistry, 305(2002): 214-226.
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