Neuropeptide Y (DP3) Aptamer Details
ID# 7806
Structure
Chemistry
DNA
Target
Neuropeptide Y (NPY)
Category
Peptide
Affinity (Kd)
370 nM
Length
90
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprGprAprGprAprAprAprGprGprGprAprAprGpnCpnUpnUprGprAprGp nCprAprGpnCprAprGprGprAprGprGprGpnCpnCprGprGpnCprGpnUpnUprAprGprGprGpnUpnUprAprGpnCprGprAprGpnCpnCprGprApnUpnUprGprAprAp rAprGprAprAprGprAprAprGprGprAprApnCprGprAprGpnCprGpnUprApnCprGprGprApnUpnCpnCprGprApnUpnCp -3'
Molecular Weight: 45033.34
Extinction Coefficient: 928300
Binding Conditions / Buffer
Binding Buffer: 0.9 mM KH2P4, Na2HPO4, 70 mM NaCL, 1.3 mM KCl, 1% heparin, 0.4 g/l of streptavidin, pH 7.6.
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
D. Proske et al. A Y2 receptor mimetic aptamer directed against neuropeptide Y. J. Biol. Chem. 277(2002):11416-11422.
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