Aptagen

Neurofilament Light Chain (tNfL-FZJ-3) Aptamer Details

ID# 9975
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Structure
Neurofilament Light Chain (tNfL-FZJ-3) structure
Chemistry
DNA
Target
Neurofilament Light Chain
Category
Protein
Affinity (Kd)
100.25 nM
Length
43
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dTpdCpdCpdCpdTpdCpdCpdApdTpdCpdTpdApdApdGpdCpdCpdTpdTpdTpdApdTpdTpdTpdCpdGpdTpdApdTpdGpdTpdCpdGpdTpdCpdGpdApdApdGpdGpdTpdGpdTpdGp-3'
Molecular Weight: 13141.5 g/mole
Extinction Coefficient: 396700

Binding Conditions / Buffer

1X PBS (No NaCl), pH 7.4, Room temperature
Binding Temp: Room temperature°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Hangyu Li, Qinyu Hu, Krisztina Percze, Mateo Alejandro Martínez Roque, Shengkai Sun, Francesca Santoro, Andreas Offenhäusser, Dirk Mayer, A label-free electrochemical aptasensor enables ultrasensitive and specific detection of neurofilament light, Biosensors and Bioelectronics, Volume 311, 2026, 118884, ISSN 0956-5663, https://doi.org/10.1016/j.bios.2026.118884.
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